@article {165,
	title = {Development of Electrically Conductive Oligo(polyethylene glycol) Fumarate-Polypyrrole Hydrogels for Nerve Regeneration.},
	journal = {Biomacromolecules},
	volume = {11},
	year = {2010},
	note = {CAPLUS AN 2010:1274866(Journal)},
	month = {2010///},
	pages = {2845 - 2853},
	publisher = {American Chemical Society},
	abstract = {Elec. conductive hydrogel composites consisting of oligo(polyethylene glycol) fumarate (OPF) and polypyrrole (PPy) were developed for applications in nerve regeneration.  OPF-PPy scaffolds were synthesized using three different anions: naphthalene-2-sulfonic acid sodium salt (NSA), dodecylbenzenesulfonic acid sodium salt (DBSA), and dioctyl sulfosuccinate sodium salt (DOSS).  Scaffolds were characterized by ATR-FTIR, XPS, AFM, dynamic mech. anal., elec. resistivity measurements, and swelling expts.  OPF-PPy scaffolds were shown to consist of up to 25 mol \% polypyrrole with a compressive modulus ranging from 265 to 323 kPa and a sheet resistance ranging from 6 to 30 {\texttimes} 103 Ohms/square.  In vitro studies using PC12 cells showed OPF-PPy materials had no cytotoxicity and PC12 cells showed distinctly better cell attachment and an increase in the percent of neurite bearing cells on OPF-PPy materials compared to OPF.  The neurite lengths of PC12 cells were significantly higher on OPF-PPyNSA and OPF-PPyDBSA.  These results show that elec. conductive OPF-PPy hydrogels are promising candidates for future applications in nerve regeneration. [on SciFinder(R)]},
	keywords = {elec conductive oligopolyethylene glycol fumarate polypyrrole hydrogel nerve regeneration},
	isbn = {1525-7797},
	author = {Runge, M. Brett and Dadsetan, Mahrokh and Baltrusaitis, Jonas and Ruesink, Terry and Lu, Lichun and Windebank, Anthony J. and Yaszemski, Michael J.}
}
