@article {165,
	title = {Development of Electrically Conductive Oligo(polyethylene glycol) Fumarate-Polypyrrole Hydrogels for Nerve Regeneration.},
	journal = {Biomacromolecules},
	volume = {11},
	year = {2010},
	note = {CAPLUS AN 2010:1274866(Journal)},
	month = {2010///},
	pages = {2845 - 2853},
	publisher = {American Chemical Society},
	abstract = {Elec. conductive hydrogel composites consisting of oligo(polyethylene glycol) fumarate (OPF) and polypyrrole (PPy) were developed for applications in nerve regeneration.  OPF-PPy scaffolds were synthesized using three different anions: naphthalene-2-sulfonic acid sodium salt (NSA), dodecylbenzenesulfonic acid sodium salt (DBSA), and dioctyl sulfosuccinate sodium salt (DOSS).  Scaffolds were characterized by ATR-FTIR, XPS, AFM, dynamic mech. anal., elec. resistivity measurements, and swelling expts.  OPF-PPy scaffolds were shown to consist of up to 25 mol \% polypyrrole with a compressive modulus ranging from 265 to 323 kPa and a sheet resistance ranging from 6 to 30 {\texttimes} 103 Ohms/square.  In vitro studies using PC12 cells showed OPF-PPy materials had no cytotoxicity and PC12 cells showed distinctly better cell attachment and an increase in the percent of neurite bearing cells on OPF-PPy materials compared to OPF.  The neurite lengths of PC12 cells were significantly higher on OPF-PPyNSA and OPF-PPyDBSA.  These results show that elec. conductive OPF-PPy hydrogels are promising candidates for future applications in nerve regeneration. [on SciFinder(R)]},
	keywords = {elec conductive oligopolyethylene glycol fumarate polypyrrole hydrogel nerve regeneration},
	isbn = {1525-7797},
	author = {Runge, M. Brett and Dadsetan, Mahrokh and Baltrusaitis, Jonas and Ruesink, Terry and Lu, Lichun and Windebank, Anthony J. and Yaszemski, Michael J.}
}
@article {172,
	title = {The development of electrically conductive polycaprolactone fumarate-polypyrrole composite materials for nerve regeneration.},
	journal = {Biomaterials},
	volume = {31},
	year = {2010},
	note = {CAPLUS AN 2010:772547(Journal)},
	month = {2010///},
	pages = {5916 - 5926},
	publisher = {Elsevier Ltd.},
	abstract = {Elec. conductive polymer composites composed of polycaprolactone fumarate and polypyrrole (PCLF-PPy) have been developed for nerve regeneration applications.  Here we report the synthesis and characterization of PCLF-PPy and in vitro studies showing PCLF-PPy materials support both PC12 cell and dorsal root ganglia (DRG) neurite extension.  PCLF-PPy composite materials were synthesized by polymg. pyrrole in preformed PCLF scaffolds (Mn 7000 or 18,000 g mol-1) resulting in interpenetrating networks of PCLF-PPy.  Chem. compns. and thermal properties were characterized by ATR-FTIR, XPS, DSC, and TGA.  PCLF-PPy materials were synthesized with five different anions (naphthalene-2-sulfonic acid sodium salt (NSA), dodecylbenzenesulfonic acid sodium salt (DBSA), dioctyl sulfosuccinate sodium salt (DOSS), potassium iodide (I), and lysine) to investigate effects on elec. cond. and to optimize chem. compn. for cellular compatibility.  PCLF-PPy materials have variable elec. cond. up to 6 mS cm-1 with bulk compns. ranging from 5 to 13.5 \% polypyrrole.  AFM and SEM characterization show microstructures with a root mean squared (RMS) roughness of 1195 nm and nanostructures with RMS roughness of 8 nm.  In vitro studies using PC12 cells and DRG show PCLF-PPy materials synthesized with NSA or DBSA support cell attachment, proliferation, neurite extension, and are promising materials for future studies involving elec. stimulation. [on SciFinder(R)]},
	keywords = {elec conductive polycaprolactone fumarate polypyrrole composite nerve regeneration},
	isbn = {0142-9612},
	author = {Brett Runge, M. and Dadsetan, Mahrokh and Baltrusaitis, Jonas and Knight, Andrew M. and Ruesink, Terry and Lazcano, Eric A. and Lu, Lichun and Windebank, Anthony J. and Yaszemski, Michael J.}
}
