@article {113,
	title = {Product-to-parent reversion of trenbolone: Unrecognized risks for endocrine disruption.},
	journal = {Science (Washington, DC, United States)},
	volume = {342},
	year = {2013},
	note = {CAPLUS AN 2013:1616444(Journal)},
	pages = {347 - 351},
	publisher = {American Association for the Advancement of Science},
	abstract = {Trenbolone acetate (TBA) is a high-value steroidal growth promoter often administered to beef cattle, whose metabolites are potent endocrine-disrupting compds.  We performed lab. and field phototransformation expts. to assess the fate of TBA metabolites and their photoproducts.  Unexpectedly, we obsd. that the rapid photohydration of TBA metabolites is reversible under conditions representative of those in surface waters (pH 7, 25{\textdegree}C).  This product-to-parent reversion mechanism results in diurnal cycling and substantial regeneration of TBA metabolites at rates that are strongly temp.- and pH-dependent.  Photoproducts can also react to produce structural analogs of TBA metabolites.  These reactions also occur in structurally similar steroids, including human pharmaceuticals, which suggests that predictive fate models and regulatory risk assessment paradigms must account for transformation products of high-risk environmental contaminants such as endocrine-disrupting steroids. [on SciFinder(R)]},
	keywords = {trenbolone metabolite reversion endocrine disruption environment risk},
	isbn = {0036-8075},
	author = {Qu, Shen and Kolodziej, Edward P. and Long, Sarah A. and Gloer, James B. and Patterson, Eric V. and Baltrusaitis, Jonas and Jones, Gerrad D. and Benchetler, Peter V. and Cole, Emily A. and Kimbrough, Kaitlin C. and Tarnoff, Matthew D. and Cwiertny, David M.}
}
@article {155,
	title = {Phomalevones A-C: Dimeric and pseudodimeric polyketides from a fungicolous Hawaiian isolate of Phoma sp. (Cucurbitariaceae).},
	journal = {Journal of Natural Products},
	volume = {74},
	year = {2011},
	note = {CAPLUS AN 2011:84225(Journal; Online Computer File)},
	month = {2011///},
	pages = {395 - 401},
	publisher = {American Chemical Society-American Society of Pharmacognosy},
	abstract = {Phomalevones A-C (1-3), three new compds. with bis-dihydroxanthone and bis-benzophenone systems, were isolated from cultures of a Hawaiian isolate of Phoma sp. (MYC-1734 = NRRL 39060; Cucurbitariaceae).  The structures of 1-3 were detd. by anal. of NMR and MS data.  The abs. configurations of the sp3 stereocenters in the monomeric unit of 1 were assigned by application of Mosher{\textquoteright}s method, and overall abs. configurations were proposed on the basis of ECD data using both computational methods and comparisons with literature data for model compds.  All three compds. showed antibacterial activity, and compds. 2 and 3 also exhibited antifungal effects. [on SciFinder(R)]},
	keywords = {phomalevone Phoma},
	isbn = {0163-3864},
	author = {Shim, Sang Hee and Baltrusaitis, Jonas and Gloer, James B. and Wicklow, Donald T.}
}
